0387300104, Pages:223
Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body. In addition
to its traditional role as a hormone that stimulates red blood cell production, in recent years many
laboratories have shown that EPO can act as a neuroprotective compound in a variety of injury paradigms
in the nervous system. Past experience with relatively safety profile of this FDA-approved drug makes
it an ideal candidate to take it into clinical trials for neuroprotection. We are on the verge of major
clinical trials using this drug for neuroprotection in diseases ranging from stroke, to transverse
myelitis to chemotherapy-induced peripheral neuropathy. This is the first book of its kind that brings
together researchers from many different disciplines of neuroscience to review the current
state-of-the-art in EPO and the nervous system. This book will benefit scientists and clinicians
interested in neuroprotection in the broadest sense.
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